Hemodialysis Acutely Improves Hepatic CYP3A4 Metabolic Activity
نویسندگان
چکیده
منابع مشابه
Hemodialysis does not alter in vitro hepatic CYP3A4 and CYP2D6 metabolic activity in uremic serum
There is a paucity of studies evaluating the change in liver metabolism in subjects receiving hemodialysis. The purpose of this study was to compare the effect of uremic toxins on hepatic cytochrome P450 (CYP)3A4 and CYP2D6 metabolism before and after a 4-hour hemodialysis session. Midazolam and dextromethorphan were incubated with uremic serum collected from subjects before and after the 4-hou...
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 2006
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.2006060610